Searchable abstracts of presentations at key conferences in endocrinology

ea0011p33 | Bone | ECE2006

Effect of grape procyanidins on TNF alpha mRNA expression and cell DNA damage in MC3T3-E1 osteoblast-like cells in vitro

Zhong JY , Zhang LH

Aim: This study was to investigate the protective effect of grape procyanidins on ethanol and carbon tetrachloride induced cell damages in MC3T3-E1 osteoblast-like cells.Methods: Normal MC3T3-E1 osteoblast-like cells and cells damaged by ethanol or carbon tetrachloride were incubated with different doses of grape procyanidins for 24 hours. Cell TNF alpha mRNA expression and apoptotic DNA fragmentation were subsequently determined using in situ hyb...